Department of Medicine

Case Western Reserve University School of Medicine & UH Case Medical Center

First multi-PI combined training program between CWRU and Cleveland Clinic headed by Fabio Cominelli

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Beginning in July, the first multiple-principal investigator combined training program between Case Western Reserve University and Cleveland Clinic will be initiated by Fabio Cominelli MD, PhD, the Hermann Menges, Jr. Chair in Internal Medicine at the School of Medicine, and Claudio Fiocchi MD¸ Clifford and Jane Anthony Chair for Digestive Disease Research and Education, Lerner Research Institute at Cleveland Clinic.
The National Institute of Diabetes, Digestive and Kidney Diseases provided the new joint effort with a five-year grant worth nearly $1M. The funding supports post-doctoral fellows in obtaining digestive disease science training for a period of three years; for physicians this will be in conjunction with their clinical training in gastroenterology.
This training program is unique in that it follows the city-based program model of the Clinical and Translational Science Collaborative (CTSC). Trainees will come to Cleveland with the option to train either at the Lerner Research Institute or the School of Medicine, and they will have the ability to choose among 20 mentors whose laboratories are supported by more than $20 million per year in National Institutes of Health funding.

CWRUmedicine To Lead Hypertension Study

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Case Western Reserve University School of Medicine is getting nearly 15 million dollars from the National Institutes of health to lead an important new study of hypertension.

Current guidelines recommend lowering hypertensive patients’ systolic blood pressure – that’s the first number in a blood pressure reading – to below 140 – 138 over 90, for example.  But physicians want to know if lowering that recommended systolic blood pressure to below 120 can further reduce the incidence of cardiovascular and kidney disease, or slow the decline of functional cognition.

Dr. Jackson Wright, who heads the Clinical Hypertension Program at University Hospitals Case Medical Center, says the medical school will be one of five U.S. institutions taking a leadership role in what’s called the Systolic Blood Pressure Intervention Trial – dubbed SPRINT.

Wright:  “The fact that Cleveland, Northeast Ohio and Central Ohio has a very diverse population makes this an outstanding location to conduct a study such as SPRINT.”

The study will take place over 9 years, and will involve 75 hundred patients.

Wright says it will measure the benefits of reducing systolic blood pressure against risks posed by increased medication and other factors in treatment of hypertension.

Learn more at CWRUmedicine.org

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1030hypertension.mp3 (396 KB)

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